| Date | Home team | Result | Guest team |
|---|---|---|---|
| 8. August 2020 16:30 | Club Brugge KV  |
0 - 1 |  Sporting Charleroi |
| 8. August 2020 19:00 | R. Antwerp FC  |
1 - 1 |  R. Excel Mouscron |
| 8. August 2020 19:00 | Standard de Liège  |
1 - 0 |  Cercle Brugge |
| 9. August 2020 13:30 | Sint Truiden VV  |
2 - 1 |  KAA Gent |
| 9. August 2020 16:00 | SV Zulte Waregem  |
1 - 2 |  KRC Genk |
| 9. August 2020 18:15 | YR KV Mechelen  |
2 - 2 |  RSC Anderlecht |
| 9. August 2020 20:45 | KV Kortrijk  |
1 - 3 |  KVRS Waasland Beveren |
| 10. August 2020 19:00 | OH Leuven  |
1 - 1 |  KAS Eupen |
| 10. August 2020 19:00 | KV Ostende  |
1 - 2 |  KFCO Beerschot Wilrijk |
* Dates not yet confirmed and therefore subject to change.